Dio Cancer Fund Announces New Partnership to Push Gastric Cancer Research Forward
via DIOCIRCLE / YouTube
The Ronnie James Dio Stand Up And Shout Cancer Fund, created in memory of the late heavy metal icon, has long been dedicated to funding innovative cancer research. Since its founding after Dio’s passing from gastric cancer in 2010, the organization has supported groundbreaking projects aimed at early detection and prevention of the disease that claimed his life.
One of its most notable collaborations has been with Dr. David T. W. Wong of UCLA’s School of Dentistry and Center for Oral/Head & Neck Oncology Research. Since 2016, Dr. Wong and his team have led pioneering work in developing non-invasive diagnostic methods for cancer detection. In recognition of Dio’s lasting legacy, UCLA recently dedicated the Saliva Storage Room in Dr. Wong’s lab to the late singer, marking another milestone in the ongoing fight against cancer.
Through years of collaboration, the Dio Cancer Fund and Dr. Wong’s lab have focused on research that could one day transform routine medical checkups into opportunities for early cancer diagnosis — potentially saving countless lives worldwide.
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The Science Behind the Breakthrough
At the center of this partnership is a revolutionary diagnostic technology called Electric Field-Induced Release and Measurement, or EFIRM. The procedure, often described as a “liquid biopsy,” enables researchers to detect cancer-related mutations through saliva rather than invasive tissue samples. This innovative approach not only simplifies cancer testing but also opens the door for widespread early detection.
Dr. Wong’s studies have already demonstrated EFIRM’s ability to identify tumor-specific genetic mutations with remarkable accuracy, particularly in cases of non-small cell lung cancer. The method isolates and analyzes biomarker signals directly from saliva and other biofluids, eliminating the need for complex lab preparation.
This simplicity and reliability make EFIRM one of the most promising diagnostic technologies in development today. With continued support from organizations like the Dio Cancer Fund, researchers aim to refine the process and bring it closer to real-world clinical use.
A New Partnership with Global Impact
The latest step forward in this mission comes with a new three-year partnership between UCLA’s School of Dentistry and South Korean semiconductor company Dongwoon Anatech. The company, known for its saliva-based glucose monitoring system D-SaLife, will contribute up to $787,500 annually to support EFIRM research. Together, they aim to enhance the system for detecting biomarkers linked to gastric, lung, and oral cancers — diseases that continue to cause significant mortality worldwide.
For South Korea in particular, gastric cancer remains one of the leading causes of death, making the collaboration especially timely. Dongwoon Anatech’s expertise in microchip technology and sensor design complements UCLA’s clinical research, creating a powerful alliance capable of accelerating EFIRM’s transition from laboratory testing to medical practice.
According to Dr. Wong, this partnership — alongside ongoing support from the Dio Cancer Fund — represents a vital step toward turning EFIRM into a fully diagnostic tool that could soon be available in doctors’ offices as part of standard physical examinations.
Honoring Dio’s Spirit Through Action
Since its founding, the Ronnie James Dio Stand Up And Shout Cancer Fund has raised more than $2.5 million for cancer research and awareness through concerts, charity events, and fan-driven initiatives. Each dollar contributes to advancing Dio’s widow Wendy Dio’s mantra: “Early detection saves lives.”
Dr. Wong’s lab continues to receive substantial funding from national institutions, including more than $29 million from the National Institutes of Health and other agencies since 2002. The Fund plans to reaffirm its commitment by presenting another donation during its upcoming annual bowling fundraiser on November 13 in Los Angeles.
For fans, Dio’s impact goes far beyond his soaring vocals and stage presence. Known for popularizing the “devil horns” hand gesture, he symbolized strength, individuality, and perseverance — qualities that now define the fight against cancer waged in his honor. Through this new global collaboration, Ronnie James Dio’s legacy continues to inspire both fans and scientists to keep standing up and shouting for a cure.
